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Index > Protein center > HSPA9(Gene name) > Human
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  • HSPA9 (Gene name),
  • Stress-70 protein, mitochondrial (Protein name ),  GRP75_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    HSPA9(GRP75;HSPA9B;mt-HSP70);
    Protein name:
    Stress-70 protein, mitochondrial;
    Alternative:
    Heat shock 70 kDa protein 9;75 kDa glucose-regulated protein(GRP-75);Peptide-binding protein 74(PBP74);Mortalin(MOT);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with FXN. Interacts with HSCB.
    Function:
    Implicated in the control of cell proliferation and cellular aging. May also act as a chaperone.
    Subcellular Location:
    Mitochondrion
    Protein Attributes:
    Sequence length:
    679
    Sequence:
    50:
    MISASRAAAA | RLVGAAASRG | PTAARHQDSW | NGLSHEAFRL | VSRRDYASEA | 
    100:
    IKGAVVGIDL | GTTNSCVAVM | EGKQAKVLEN | AEGARTTPSV | VAFTADGERL | 
    150:
    VGMPAKRQAV | TNPNNTFYAT | KRLIGRRYDD | PEVQKDIKNV | PFKIVRASNG | 
    200:
    DAWVEAHGKL | YSPSQIGAFV | LMKMKETAEN | YLGHTAKNAV | ITVPAYFNDS | 
    250:
    QRQATKDAGQ | ISGLNVLRVI | NEPTAAALAY | GLDKSEDKVI | AVYDLGGGTF | 
    300:
    DISILEIQKG | VFEVKSTNGD | TFLGGEDFDQ | ALLRHIVKEF | KRETGVDLTK | 
    350:
    DNMALQRVRE | AAEKAKCELS | SSVQTDINLP | YLTMDSSGPK | HLNMKLTRAQ | 
    400:
    FEGIVTDLIR | RTIAPCQKAM | QDAEVSKSDI | GEVILVGGMT | RMPKVQQTVQ | 
    450:
    DLFGRAPSKA | VNPDEAVAIG | AAIQGGVLAG | DVTDVLLLDV | TPLSLGIETL | 
    500:
    GGVFTKLINR | NTTIPTKKSQ | VFSTAADGQT | QVEIKVCQGE | REMAGDNKLL | 
    550:
    GQFTLIGIPP | APRGVPQIEV | TFDIDANGIV | HVSAKDKGTG | REQQIVIQSS | 
    600:
    GGLSKDDIEN | MVKNAEKYAE | EDRRKKERVE | AVNMAEGIIH | DTETKMEEFK | 
    650:
    DQLPADECNK | LKEEISKMRE | LLARKDSETG | ENIRQAASSL | QQASLKLFEM | 
    679:
    AYKKMASERE | GSGSSGTGEQ | KEDQKEEKQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    Pfam:
    SMR:
    KEGG:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Stress-70 protein, mitochondrial
    Cat.:
    E9060h
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    ELISA Kit for Human Stress-70 protein, mitochondrial
    Cat.:
    E9060m
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    Packing:
    96T
    ELISA Kit for Human Stress-70 protein, mitochondrial
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    E9060d
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    ELISA Kit for Human Stress-70 protein, mitochondrial
    Cat.:
    E9060b
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    ELISA Kit for Human Stress-70 protein, mitochondrial
    Cat.:
    E9060c
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    ELISA Kit for Human Stress-70 protein, mitochondrial
    Cat.:
    E9060r
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    Packing:
    96T
    CLIA Kit for Human Stress-70 protein, mitochondrial
    Cat.:
    U9060d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Stress-70 protein, mitochondrial
    Cat.:
    U9060b
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    Packing:
    96T
    CLIA Kit for Human Stress-70 protein, mitochondrial
    Cat.:
    U9060c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Stress-70 protein, mitochondrial
    Cat.:
    U9060r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Stress-70 protein, mitochondrial
    Cat.:
    U9060h
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Stress-70 protein, mitochondrial
    Cat.:
    U9060m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Stress-70 protein, mitochondrial
    Polyclonal Antibody for Human Stress-70 protein, mitochondrial
    Cat.:
    P9060Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Stress-70 protein, mitochondrial
    Cat.:
    P9060Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Stress-70 protein, mitochondrial
    Cat.:
    P9060Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Stress-70 protein, mitochondrial
    Polyclonal Antibody for Human Stress-70 protein, mitochondrial
    Monoclonal Antibody for Human Stress-70 protein, mitochondrial
    Monoclonal Antibody for Human Stress-70 protein, mitochondrial
    Monoclonal Antibody for Human Stress-70 protein, mitochondrial
    Monoclonal Antibody for Human Stress-70 protein, mitochondrial
    Monoclonal Antibody for Human Stress-70 protein, mitochondrial
    Monoclonal Antibody for Human Stress-70 protein, mitochondrial
    Protein for Human Stress-70 protein, mitochondrial
    Protein for Human Stress-70 protein, mitochondrial
    Protein for Human Stress-70 protein, mitochondrial
    Protein for Human Stress-70 protein, mitochondrial
    Protein for Human Stress-70 protein, mitochondrial
    Protein for Human Stress-70 protein, mitochondrial

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning of the gene encoding peptide-binding protein 74 shows that it is a new member of the heat shock protein 70 family."
      Domanico S.Z. , Denagel D.C. , Dahlseid J.N. , Green J.M. , Pierce S.K.
      Mol. Cell. Biol.13:3598-3610(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: B-cell.
    2. 2.
      "Cloning and subcellular localization of human mitochondrial hsp70."
      Bhattacharyya T. , Karnezis A.N. , Murphy S.P. , Hoang T. , Freeman B.C. , Phillips B. , Morimoto R.I.
      J. Biol. Chem.270:1705-1710(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Teratocarcinoma.
    4. 4.
      Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
      Submitted (2005-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Liver.
    5. 5.
      NIEHS SNPs program
      Submitted (2006-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT TYR-184
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ARG-74
      tissue: Muscle.
    8. 8.
      "A two-dimensional gel database of human colon carcinoma proteins."
      Ji H. , Reid G.E. , Moritz R.L. , Eddes J.S. , Burgess A.W. , Simpson R.J.
      Electrophoresis18:605-613(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 47-68
      tissue: Colon carcinoma.
    9. 9.
      "Analysis of proteins from human breast epithelial cells using two-dimensional gel electrophoresis."
      Giometti C.S. , Tollaksen S.L. , Chubb C. , Williams C. , Huberman E.
      Electrophoresis16:1215-1224(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 47-66
      tissue: Mammary gland.
    10. 10.
      "Human liver protein map: a reference database established by microsequencing and gel comparison."
      Hochstrasser D.F. , Frutiger S. , Paquet N. , Bairoch A. , Ravier F. , Pasquali C. , Sanchez J.-C. , Tissot J.-D. , Bjellqvist B. , Vargas R. , Appel R.D. , Hughes G.J.
      Electrophoresis13:992-1001(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 47-56
      tissue: Liver.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
      tissue: Liver.
    12. 12.
      Lubec G. , Afjehi-Sadat L. , Chen W.-Q. , Sun Y.
      Submitted (2008-12) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 86-99; 108-121; 160-173; 188-202; 207-234; 349-360; 378-391; 395-405; 469-485; 499-513 AND 542-555;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Brain.
      tissue: Cajal-Retzius cell.
      tissue: Fetal brain cortex.
    13. 13.
      "Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones."
      Shan Y. , Napoli E. , Cortopassi G.
      Hum. Mol. Genet.16:929-941(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FXN
    14. 14.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-135; LYS-138; LYS-143; LYS-234; LYS-288; LYS-300; LYS-567 AND LYS-646;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 15.
      "Characterization of the human HSC20, an unusual DnaJ type III protein, involved in iron-sulfur cluster biogenesis."
      Uhrigshardt H. , Singh A. , Kovtunovych G. , Ghosh M. , Rouault T.A.
      Hum. Mol. Genet.19:3816-3834(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HSCB
    16. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    17. 17.
      "The first identification of lysine malonylation substrates and its regulatory enzyme."
      Peng C. , Lu Z. , Xie Z. , Cheng Z. , Chen Y. , Tan M. , Luo H. , Zhang Y. , He W. , Yang K. , Zwaans B.M. , Tishkoff D. , Ho L. , Lombard D. , He T.C. , Dai J. , Verdin E. , Ye Y. , more...
      Mol. Cell. Proteomics10:M111.012658.01-M111.012658.12(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MALONYLATION AT LYS-206
    18. 18.
      "MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization."
      Alkhaja A.K. , Jans D.C. , Nikolov M. , Vukotic M. , Lytovchenko O. , Ludewig F. , Schliebs W. , Riedel D. , Urlaub H. , Jakobs S. , Deckers M.
      Mol. Biol. Cell23:247-257(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE MINOS/MITOS COMPLEX
    19. 19.
      "Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization."
      Ahmad Y. , Boisvert F.M. , Lundberg E. , Uhlen M. , Lamond A.I.
      Mol. Cell. Proteomics11:M111.013680.01-M111.013680.15(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
    20. 20.
      "Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium flux."
      Matsuzaki H. , Fujimoto T. , Tanaka M. , Shirasawa S.
      Biochem. Biophys. Res. Commun.433:322-326(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH TESPA
    21. 21.
      "Structural and stability studies of the human mtHsp70-escort protein 1: An essential mortalin co-chaperone."
      Dores-Silva P.R. , Minari K. , Ramos C.H. , Barbosa L.R. , Borges J.C.
      Int. J. Biol. Macromol.56:140-148(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DNLZ
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